PQNS Platform

Next-Gen Phytosome Quantum Nano Sphere for Advanced Bioactive Delivery

A cationic phospholipid vesicle system engineered to improve solubility, stability, absorption, and gut tolerance for minerals, vitamins, botanicals, and key bioactives.

Why PQNS

Protection, Precision, and Programmable Release

Designed to mirror biological membranes and optimize cellular uptake while reducing GI irritation.

Enhanced Solubility

Encapsulation improves dissolution of low-solubility actives and shields them from degradation.

Targeted Uptake

Surface charge and ligand options promote membrane interaction and receptor-mediated delivery.

Gut-Friendly Profile

Vesicular barrier reduces direct ion contact with the intestinal lining for better tolerability.

PQNS vesicle illustration
Mechanism

Phytosome Quantum Nano Sphere (PQNS)

  • Encapsulation: Bioactives loaded in an aqueous core or bilayer for stability and controlled exposure.
  • Positive Surface Charge: Promotes electrostatic interactions with enterocyte membranes and uptake.
  • Multiple Entry Paths: Membrane fusion, passive diffusion, endocytosis, and receptor-mediated routes.
  • Shielding: Protects contents from gastric acidity and enzymatic degradation for higher effective delivery.
Baseline Bioavailability

Where PQNS Can Help Most

Selected ingredients with typically low raw bioavailability—ideal candidates for PQNS formulation.

CategoryExamplesRaw Bioavailability
BotanicalsCurcumin, Resveratrol, Quercetin, EGCGVery low
MineralsIronLow
VitaminsVitamin K1/K2Moderate
Other BioactivesCoQ10, Omega-3 (EPA/DHA)Very low

Note: Values represent typical ranges for raw actives prior to PQNS enhancement.

Cell membrane phospholipid bilayer illustration

Why PQNS

Clinically-minded delivery that patients tolerate

Superior Tolerability

Reduces gastrointestinal irritation vs. conventional supplements.

Improved Absorption

Phospholipid encapsulation enhances nutrient solubility.

Increased Bioavailability

PQNS boosts systemic uptake up to ~85–90%.

Biocompatibility & Safety

Mimics natural cell membranes for gut-friendly delivery.

Controlled Release

Ensures steady nutrient levels and reduced dosing frequency.

Gallery

Visualizing the Platform

PQNS concept image 1
PQNS concept image 2
PQNS concept image 3
Get the Technical Details

Ready to evaluate PQNS for your formula?

Request the technical deck, CoAs, and a feasibility discussion with our R&D.

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