Q-Antifungal
Phyto-Nanogel
A Scientifically Engineered, Multi-Targeted Topical Therapy for Fungal Skin Infections and Skin Barrier Restoration.
Prepared for: Crassula Cosmeceutical Division
"Targeting Infection. Restoring Skin Health."
by Day 14
by Day 7
Clinical Study
Events
Executive Summary
A New Standard for
Antifungal Therapy
Fungal skin infections represent a rapidly growing global health challenge, driven by rising antifungal resistance, recurrence, prolonged treatment durations, and increasing populations of immunocompromised individuals.
Q-ANTIFUNGAL Gel integrates antifungal, anti-inflammatory, immunomodulatory, regenerative, and barrier-restorative mechanisms in a single non-steroidal formulation.
Indications
Rapid, Proven Results
Clinical evidence demonstrates rapid symptom relief, high clinical cure rates, excellent safety, and meaningful improvements in skin texture and patient satisfaction across 60 clinically evaluated patients.
1. Clinical Background & Unmet Need
Key Drivers of Increasing
Fungal Infections
Superficial and subcutaneous fungal infections affect the skin, keratinous tissues, hair shafts, and mucous membranes, resulting in itching, erythema, scaling, discharge, malodour, and lesion expansion.
- High humidity and temperature environments
- Poor hygiene and overcrowding
- Rising antifungal resistance
- Misuse of topical steroid–antifungal combinations
- Incomplete treatment adherence
- Prolonged treatment duration
- Burning and irritation
- High recurrence rates after discontinuation
- Steroid-related complications
- Limited skin regeneration support
3. Scientific Rationale
Multi-Pathway Mechanism of Action
Q-ANTIFUNGAL is engineered as a multi-pathway antifungal and skin-healing system. This integrated mechanism enables pathogen clearance while simultaneously restoring skin health.
4. Proprietary Formulation Architecture
Key Bioactive Components
This proprietary blend normalizes the skin microenvironment at the cellular level through four synergistic functional groups.
Nanoparticle Technology
Copper and silver nanoparticles provide dual-action antimicrobial coverage, penetrating biofilms and disrupting fungal membrane integrity while enhancing delivery of botanical actives to infected tissue layers. Powered by QuanticSphere™ PQNS technology for controlled, targeted release.
Antifungal & Antimicrobial Mechanism
This botanical complex disrupts fungal cell membranes, inhibits biofilm formation, and provides broad-spectrum coverage against dermatophytes, yeasts, and bacteria — without inducing resistance or requiring antibiotic actives.
Anti-Inflammatory & Immunomodulatory Mechanism
These agents downregulate inflammatory pathways including NF-κB and 5-LOX signaling, reducing the erythema, pruritus, and edema that characterize active fungal infections while supporting local immune defense.
Skin Repair & Barrier Mechanism
Promote fibroblast activity, extracellular matrix regeneration, and microbiome normalization — restoring skin texture, reducing post-inflammatory pigmentation, and preventing recurrence by reestablishing a healthy skin barrier.
Role of QuanticSphere™ PQNS Technology
Advanced Delivery System
Q-ANTIFUNGAL integrates phospholipid-based PQNS vesicles to enhance topical performance. PQNS provides delivery precision without systemic exposure, aligning with medical-grade dermatologic safety standards.
5–7. Clinical Study
Rigorous Clinical Evaluation
| Parameter | Detail |
|---|---|
| Study Type | Prospective, open-label, single-arm clinical observational study |
| Setting | Outpatient dermatology clinics |
| Population | 60 patients with clinically diagnosed ringworm (tinea corporis) |
| Age Range | 18–65 years |
| Regimen | Topical application twice daily for 14 days |
| Assessments | Day 0 (baseline), Day 7, Day 14 |
| Scoring | 0–3 scale: itching, redness, scaling, discharge, malodour, lesion size, skin texture |
| Cure Definition | Score 0 all symptoms · No active lesion margins · No itching or erythema |
Marked improvement
Complete clinical cure
Symptom Score Reduction
8. Safety & Tolerability
Excellent Safety Profile
Q-ANTIFUNGAL Gel was found to be safe and well tolerated across all 60 subjects throughout the full 14-day evaluation period.
Next-Generation
Antifungal Therapy
Q-ANTIFUNGAL Gel is a medical-grade, scientifically engineered phyto-nanogel designed to eliminate fungal skin infections, reduce inflammation and recurrence, and restore the skin microenvironment through a multi-target, technology-driven approach.
Contact the Medical Team