Q-Hairgrowth Serum | Crassula Cosmeceutical Division
Crassula Cosmeceutical Division · QuanticSphere™ PQNS

Q-Hairgrowth
Serum

A Multi-Targeted Topical Therapy for Hair Fall Control and Follicular Regeneration. Clinical Evaluation of Safety and Efficacy in Male Subjects with Hair Fall and Early Alopecia.

"Advanced hair regrowth through follicular science."

Q-HAIRGROWTH Serum application on scalp
0%
Hair Fall Control
by Week 3
0
Male Subjects
Clinical Study
0 wks
Study Duration
Complete Results
0
Serious Adverse
Events

Clinically Proven
Hair Fall Control

Q-Hairgrowth Serum is a scientifically engineered, multi-component topical formulation designed to activate hair follicle stem cells (HFSCs), inhibit DHT-mediated follicular miniaturization, reduce oxidative stress, and restore the scalp microenvironment.

8-Week Human Clinical Study

7–10 days
Rapid hair fall reduction starts within first week
≈80–95%
Hair fall control achieved by Week 3
Weeks 6–8
Progressive new hair growth and density improvement
Excellent
Safety and tolerability — no serious adverse events

The results validate Q-Hairgrowth as an advanced non-drug topical therapy for hair fall control and follicular rejuvenation.

A prospective, open-label, single-arm 8-week human clinical study in 40 male subjects aged 25–40 years conducted in compliance with ICH-GCP principles.

The formulation's multi-pathway approach — combining antioxidants, peptides, botanical DHT blockers, and microcirculatory enhancers — creates a regenerative follicular environment, rather than a purely stimulatory effect.

Why Hair Loss
Requires a Multi-Target Approach

Alopecia affects 60–70% of adult males worldwide, with onset frequently beginning between 25–40 years. Male pattern hair loss is driven by a multifactorial pathophysiology.

Elevated DHT Activity
Elevated dihydrotestosterone (DHT) binds to follicular receptors causing progressive miniaturization.
Shortening of the Anagen (Growth) Phase
The active growth phase shortens progressively, reducing hair length and thickness over time.
Progressive Follicular Miniaturization
Hair follicles shrink gradually until they can no longer support terminal hair growth.
Oxidative Stress & Micro-Inflammation
Chronic scalp inflammation and ROS damage the follicular microenvironment.
Loss or Dormancy of HFSCs
Hair follicle stem cells in the bulge region become dormant, halting the regenerative cycle.
The Problem with Current Therapies: Conventional therapies often target only one mechanism (e.g., vasodilation or hormonal modulation), resulting in incomplete or transient benefits.
Hair loss concern — clinical background

5 Core Mechanistic
Pillars

Q-Hairgrowth was formulated as a multi-pathway biological system designed to restore the follicular ecosystem rather than merely stimulate hair shafts. This integrated strategy aligns with current advances in hair biology emphasizing HFSC reactivation.

Hair Follicle Stem Cell Activation
DHT Modulation (5-α-reductase Inhibition)
Antioxidant & Anti-Inflammatory Protection
Enhanced Scalp Microcirculation
Nutrient & Peptide-Driven Follicular Repair

Functional Ingredient
Architecture

Q-Hairgrowth Serum is a topical formulation comprising six functional ingredient categories working in synergy to address every pathway of hair loss.

HFSC Activators
  • Redensyl® (patented HFSC activator)
  • Biotinyl-GHK (bioactive peptide complex)
DHT Modulators
  • Saw palmetto extract
  • Biochanin-rich isoflavones
  • Trifolium pratense (red clover)
Antioxidants
  • Resveratrol · Quercetin · Astaxanthin
  • Lycopene · Beta-carotene · CoQ10
Microminerals & Amino Acids
  • Zinc · L-arginine · L-lysine
  • L-tryptophan · N-acetyl cysteine
Essential Oils
  • Cedarwood · Castor · Coconut · Cinnamon
  • Olive · Sesame · Bay oil
Botanical Extracts
  • Trigonella · Bacopa · Gotu kola
  • Punica granatum · Papaya · Rosemary

Rigorous Clinical Evaluation
— 8 Weeks, 40 Subjects

Study Design
Type
Open-label, single-arm, prospective clinical trial
Subjects
40 male subjects, ages 25–40 years
Duration
8 weeks
Standards
Conducted in compliance with ICH-GCP principles
Inclusion
Active hair fall (>50 hairs/day), mild to moderate alopecia, healthy scalp
Exclusion
Severe/scarring alopecia, recent PRP/transplant, systemic hair growth medications
Application Protocol
Study PeriodFrequencyContact Time
Week 1Once daily3–4 hours
Week 2Alternate days3–4 hours
Weeks 3–8Twice weekly3–4 hours
Clinical Endpoints
Efficacy
Hair fall count · Hair density · Shaft thickness · New growth
Safety
Scalp irritation · Redness/itching · Adverse events

Efficacy & Safety
Measurement Framework

Subjects were instructed not to wash the scalp during the application window. All assessments were conducted at baseline, Week 3, Week 6, and Week 8.

Efficacy Endpoints
  • Hair fall count (comb test)
  • Hair density (investigator scoring)
  • Hair shaft thickness
  • New hair growth (vellus → terminal)
Safety Endpoints
  • Scalp irritation assessment
  • Redness, itching, burning
  • Adverse event reporting
Natural botanical ingredients — coconut, cinnamon, botanical extracts

Hair Fall Reduction &
Density Recovery Over 8 Weeks

Hair Fall vs % Improvement — Mean Values
ParameterBaselineWeek 3Week 8
Hair fall90–130/day10–30/day2–8/day
Scalp visibilityHighModerateMinimal
Hair densityLowModerateHigh
Days 7–10
Rapid hair fall reduction begins — consistent with early anti-inflammatory effects and DHT modulation.
Week 3
≈80–95% hair fall control achieved. Early vellus hair appearance noted by investigators.
Week 6
Visible new hair growth emerging. Improved scalp coverage observed.
Week 8
Marked improvement in density and coverage. Hair thickness improved from thin to thicker shafts.
Hair thickness improved from thin to thicker shafts across all subjects. The progressive growth aligns with the biological timeline of HFSC activation and anagen restoration.

Excellent Safety Profile
Across All 40 Subjects

Q-Hairgrowth Serum demonstrated an outstanding safety profile throughout the 8-week study period with no clinically significant adverse effects.

No Serious Adverse Events
No serious adverse events reported throughout the full 8-week evaluation period across all 40 subjects.
Mild Warming or Tingling (~5%)
Only in ~5% of subjects during initial applications — mild and transient in nature.
All Sensations Self-Resolved
All sensations resolved spontaneously without discontinuation — 100% study completion.
The rapid reduction within 7–10 days is consistent with early anti-inflammatory effects and DHT modulation. The progressive hair growth at Weeks 6–8 aligns with the biological timeline of HFSC activation and anagen restoration.
Q-HAIRGROWTH Serum bottle — cosmeceutical product

Advanced Hair Regrowth
Through Follicular Science

Q-Hairgrowth Serum is a scientific-grade cosmeceutical for hair fall control and early-stage alopecia, designed to activate hair follicle stem cells, modulate DHT, and restore the scalp microenvironment through a multi-target, technology-driven approach.

Contact the Medical Team