{"id":11479,"date":"2026-07-16T17:58:41","date_gmt":"2026-07-16T21:58:41","guid":{"rendered":"https:\/\/crassulapharma.com\/?p=11479"},"modified":"2026-07-19T19:03:43","modified_gmt":"2026-07-19T23:03:43","slug":"q-niflex-and-pqns-technology","status":"publish","type":"post","link":"https:\/\/crassulapharma.com\/es\/q-niflex-and-pqns-technology\/","title":{"rendered":"Q-NiFlex\u2122\u00a0and Phytosome Quantum Nano Sphere (PQNS\u2122) Technology: A Next-Generation Multi-Target Drug Delivery Strategy for Joint Health and Osteoarthritis Management"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"11479\" class=\"elementor elementor-11479\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-132a97a5 e-flex e-con-boxed e-con e-parent\" data-id=\"132a97a5\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-25849cd7 elementor-widget elementor-widget-spacer\" data-id=\"25849cd7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-324a40a7 elementor-widget elementor-widget-heading\" data-id=\"324a40a7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Q-NiFlex\u2122 and Phytosome Quantum Nano Sphere (PQNS) Technology: A Next-Generation Multi-Target Drug Delivery Strategy for Joint Health and Osteoarthritis Management<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3354926b elementor-widget elementor-widget-spacer\" data-id=\"3354926b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6abc9eb1 e-flex e-con-boxed e-con e-parent\" data-id=\"6abc9eb1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6388a323 elementor-widget elementor-widget-theme-post-featured-image elementor-widget-image\" data-id=\"6388a323\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"theme-post-featured-image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/crassulapharma.com\/wp-content\/uploads\/elementor\/thumbs\/q-niflex-pqns-rqjudlfu4b4ka9eet06wxgg8rqdvel2vc66e56q70g.jpg\" title=\"q-niflex-pqns\" alt=\"q-niflex-pqns\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e5ba261 e-flex e-con-boxed e-con e-parent\" data-id=\"e5ba261\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-08e1417 elementor-widget elementor-widget-post-info\" data-id=\"08e1417\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-20e7843 elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-custom\">\n\t\t\t\t\t\t\t\t\t\tIssue - 07 | \t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-9e77c1d elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-custom\">\n\t\t\t\t\t\t\t\t\t\tJuly - 2026 | \t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-9b16684 elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-custom\">\n\t\t\t\t\t\t\t\t\t\tPRINT ISSN No. 2277 - 8179\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-01d1bdd elementor-widget elementor-widget-text-editor\" data-id=\"01d1bdd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Published review outlines the multi-target formulation and nano-delivery mechanism; a 500-patient randomized controlled trial is underway to evaluate clinical outcomes<\/p><p>A peer-reviewed paper published in the International Journal of Scientific Research (Vol. 15, Issue 7, July 2026; DOI: 10.36106\/ijsr) outlines the scientific rationale behind Q-NiFlex<sup style=\"font-size: 10px;\">TM<\/sup>, a multi-component nutraceutical for joint health, and its proprietary Phytosome Quantum Nano Sphere (PQNS) delivery technology.<\/p><p>The paper, authored by Dr. Pallavi Singh (BDS, MDS, Government Hospital, Indore, M.P.) and Dr. Raj Bhan Singh (MD Anesthesiology, Assistant Professor, ESIC Medical College &amp; Hospital, Indore, M.P.), reviews how PQNS combines phytosome complexation with nano-sized vesicular delivery \u2014 an approach intended to improve the stability, gastrointestinal protection, and systemic bioavailability of phytoconstituents that are otherwise poorly absorbed, such as curcumin and other botanical extracts.<\/p><p>Q-NiFlex<sup style=\"font-size: 10px;\">TM<\/sup> combines glucosamine sulphate, chondroitin sulphate, hyaluronic acid, Boswellia serrata, Curcuma longa, Cissus quadrangularis, and a range of complementary botanicals, amino acids, vitamins, and minerals in a once-daily tablet, formulated to address five functional domains relevant to osteoarthritis: structural cartilage support, inflammation modulation, oxidative stress reduction, connective tissue regeneration, and delivery optimization.<\/p><p>\u201cOsteoarthritis is a multifactorial condition, and single-ingredient supplements have struggled to address that complexity,\u201d the authors note in the paper. \u201cQ-NiFlex<sup style=\"font-size: 10px;\">TM<\/sup> was developed on a multi-target philosophy, and PQNS is the delivery system intended to make that formulation more bioavailable.\u201d<\/p><h4><strong>Clinical study underway<\/strong><\/h4><p>The paper is explicit that mechanistic rationale is not the same as clinical proof. A prospective, randomized, placebo-controlled study is currently underway to evaluate the efficacy and safety of Q-NiFlex<sup style=\"font-size: 10px;\">TM<\/sup> in approximately 500 osteoarthritis patients, with a 12-week treatment period and follow-up to 16 weeks. Primary endpoints include change in WOMAC score from baseline; secondary endpoints include VAS pain scores, physician global assessment, and safety labs.<\/p><p>\u201cIndependent, peer-reviewed clinical trial results will be essential to validate the proposed advantages of PQNS technology,\u201d the authors write. No efficacy claims are made pending that trial\u2019s results.<\/p><h4><strong>About the PQNS platform<\/strong><\/h4><p>PQNS is a phytosome- and nano-vesicular delivery platform developed by Integria Care, designed to improve the absorption and stability of poorly bioavailable actives.<\/p><p>Source: News By Wire<br \/><a href=\"https:\/\/newsbywire.com\/eer-reviewed-paper-details-phytosome-quantum-nano-sphere-pqns-delivery-platform-behind-q-niflex-joint-health-nutraceutical\/\" target=\"_blank\" rel=\"noopener\">https:\/\/newsbywire.com\/eer-reviewed-paper-details-phytosome-quantum-nano-sphere-pqns-delivery-platform-behind-q-niflex-joint-health-nutraceutical\/<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-71de015 e-grid e-con-boxed e-con e-parent\" data-id=\"71de015\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div 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