{"id":11991,"date":"2026-10-21T11:54:39","date_gmt":"2026-10-21T15:54:39","guid":{"rendered":"https:\/\/crassulapharma.com\/?page_id=11991"},"modified":"2026-10-21T12:12:03","modified_gmt":"2026-10-21T16:12:03","slug":"plaxam","status":"publish","type":"page","link":"https:\/\/crassulapharma.com\/es\/plaxam\/","title":{"rendered":"Plaxam"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"11991\" class=\"elementor elementor-11991\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8826718 e-con-full e-flex e-con e-parent\" data-id=\"8826718\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6c44baa elementor-widget elementor-widget-html\" data-id=\"6c44baa\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<!doctype html>\n<html lang=\"en\">\n<head>\n<meta charset=\"utf-8\">\n<meta name=\"viewport\" content=\"width=device-width, initial-scale=1\">\n<title>Plaxam\u00ae (Tranexamic Acid) \u2013 Crassula<\/title>\n<meta name=\"description\" content=\"PLAXAM is a tranexamic acid injection that helps prevent and treat haemorrhage associated with general or local fibrinolysis, according to the approved product information.\">\n<link rel=\"preload\" href=\"fonts\/poppins-latin-600-normal.woff2\" as=\"font\" type=\"font\/woff2\" crossorigin>\n<link rel=\"preload\" href=\"fonts\/ibm-plex-sans-latin-400-normal.woff2\" as=\"font\" type=\"font\/woff2\" crossorigin>\n<style>\n@font-face{font-family:\"Poppins\";font-weight:500;font-style:normal;font-display:swap;src:url(fonts\/poppins-latin-500-normal.woff2) format(\"woff2\")}\n@font-face{font-family:\"Poppins\";font-weight:600;font-style:normal;font-display:swap;src:url(fonts\/poppins-latin-600-normal.woff2) format(\"woff2\")}\n@font-face{font-family:\"IBM Plex Sans\";font-weight:400;font-style:normal;font-display:swap;src:url(fonts\/ibm-plex-sans-latin-400-normal.woff2) format(\"woff2\")}\n@font-face{font-family:\"IBM Plex Sans\";font-weight:500;font-style:normal;font-display:swap;src:url(fonts\/ibm-plex-sans-latin-500-normal.woff2) format(\"woff2\")}\n\n:root{\n  --teal-deep:#3e0b2e; --teal-head:#6b1452; --teal:#821e62; --teal-2:#942a73; --teal-3:#6b1452;\n  --red:#2c1b43; --accent-text:#6b1452; --green:#a8457f;\n  --action-teal:#821e62; --ink:#3a0f2c; --ink-muted:#5e4a58; --surface:#faf4f8; --note:#faf4f8;\n  --line:#ecdfe8;\n  --ease-out:cubic-bezier(.23,1,.32,1);\n  --font-head:\"Poppins\",system-ui,sans-serif;\n  --font-body:\"IBM Plex Sans\",system-ui,sans-serif;\n  --cx-gutter:clamp(20px,5vw,48px);\n  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dd{color:var(--teal);transform:translateX(3px)}\n}\n.ico{flex:none;width:42px;height:42px;border-radius:50%;background:var(--action-teal);display:grid;place-items:center;color:#fff}\n.ico svg{width:20px;height:20px;stroke:currentColor;fill:none;stroke-width:1.8;stroke-linecap:round;stroke-linejoin:round}\n.specs dt{font:500 11px\/1.2 var(--font-body);letter-spacing:.12em;text-transform:uppercase;color:var(--ink-muted)}\n.specs dd{font:600 15.5px\/1.3 var(--font-head);margin-top:4px;color:var(--ink)}\n@media (max-width:900px){.specs ul{grid-template-columns:1fr 1fr}.specs li:nth-child(3){border-left:0}.specs li:nth-child(n+3){border-top:1px solid var(--line)}}\n@media (max-width:480px){.specs ul{grid-template-columns:1fr}.specs li{border-left:0!important}.specs li+li{border-top:1px solid var(--line)}}\n\n\/* Sections *\/\nsection{padding-block:clamp(56px,8vw,96px)}\n.h2{color:var(--teal-head);display:flex;align-items:center;gap:14px;font:600 clamp(28px,4vw,36px)\/1.15 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\"https:\/\/schema.org\", \"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"What is Plaxam?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"PLAXAM is a tranexamic acid injection that helps prevent and treat haemorrhage associated with general or local fibrinolysis, according to the approved product information.\"}}, {\"@type\": \"Question\", \"name\": \"What is Plaxam indicated for?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"For prevention and treatment of haemorrhages due to general or local fibrinolysis in adults and children from one year of age. This includes menorrhagia and metrorrhagia (management of bleeding associated with general or local fibrinolysis), surgical procedures (including ENT, gynaecological, thoracic, abdominal and cardiovascular surgery), gastrointestinal and urinary bleeding (for haemorrhage in gastrointestinal or haemorrhagic urinary disorders when clinically indicated) and fibrinolytic agent-related haemorrhage (management of haemorrhage due to the administration of a fibrinolytic agent).\"}}, {\"@type\": \"Question\", \"name\": \"How does Plaxam work?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Tranexamic acid exerts anti-haemorrhagic activity by inhibiting the fibrinolytic properties of plasmin. By inhibiting plasmin fibrinolytic activity, tranexamic acid helps preserve fibrin clot stability.\"}}, {\"@type\": \"Question\", \"name\": \"How is Plaxam dosed and administered?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"For local fibrinolysis: 0.5 g (one 5 mL ampoule) by slow intravenous injection, two to three times daily, unless otherwise prescribed. For general fibrinolysis: 1 g (two 5 mL ampoules) by slow intravenous injection every 6 to 8 hours, equivalent to 15 mg\/kg body weight. Administration is strictly limited to slow intravenous injection. Do not administer by the intramuscular route.\"}}, {\"@type\": \"Question\", \"name\": \"How is Plaxam eliminated?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Tranexamic acid is excreted mainly unchanged in urine; reduce dosage in mild to moderate renal impairment and do not use in severe renal impairment.\"}}, {\"@type\": \"Question\", \"name\": \"What are the safety and precautionary measures for Plaxam?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Contraindicated in acute venous or arterial thrombosis. Assess thromboembolic risk factors before use. Use slow intravenous injection only. Contraindicated in severe renal impairment and history of convulsions. Monitor possible visual disturbances.\"}}, {\"@type\": \"Question\", \"name\": \"Which strength and presentations are available?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Plaxam contains tranexamic acid 500 mg \/ 5 mL and is presented in boxes of 5 or 50 ampoules (5 ampoules of 5 mL or 50 ampoules of 5 mL) for slow intravenous injection. The shelf life is 36 months.\"}}, {\"@type\": \"Question\", \"name\": \"How is Plaxam manufactured?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Each 5 mL amber glass ampoule contains tranexamic acid BP 500 mg as a clear, colourless injection. The finished-product specification includes BP identity, assay, pH, related substances and bacterial endotoxins testing. Crassula Pharma certifies that all our products are manufactured in accordance with GMP parameters.\"}}]}<\/script>\n<\/head>\n<body class=\"no-js\">\n<a class=\"skip\" href=\"#main\">Skip to content<\/a>\n<span id=\"top\"><\/span>\n\n\n<main id=\"main\">\n<section class=\"hero\" aria-labelledby=\"h1\" style=\"padding:0\">\n  <canvas id=\"fx\" aria-hidden=\"true\"><\/canvas>\n  <div class=\"cx-wrap\">\n    <div class=\"hero-copy\">\n      <span class=\"tag\">Antifibrinolytic \u00b7 Haemorrhage Management<\/span>\n      <h1 id=\"h1\">Plaxam<sup>\u00ae<\/sup><\/h1>\n      <p class=\"generic\">Tranexamic Acid<\/p>\n      <div class=\"strengths\" role=\"list\">\n        <span class=\"chip g\" role=\"listitem\">500 mg \/ 5 mL<\/span>\n      <\/div>\n      <div class=\"cta-row\">\n        <a class=\"btn btn-primary\" href=\"#mechanism\">Pharmacological Properties<\/a>\n      <\/div>\n    <\/div>\n    <div class=\"hero-art\">\n      <img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/crassulapharma.com\/wp-content\/uploads\/2026\/10\/box-plaxam.png\" alt=\"Plaxam tranexamic acid 500 mg \/ 5 mL box\" width=\"1002\" height=\"648\" title=\"\">\n    <\/div>\n  <\/div>\n<\/section>\n\n<div class=\"specs\">\n  <div class=\"cx-wrap\">\n    <ul>\n      <li><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><rect x=\"2.5\" y=\"8\" width=\"19\" height=\"8\" rx=\"4\"\/><path d=\"M12 8v8\"\/><\/svg><\/span><dl><dt>Active ingredient<\/dt><dd>Tranexamic Acid<\/dd><\/dl><\/li>\n      <li><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><path d=\"M12 12c-2-3-3.5-4-5.5-4a4 4 0 0 0 0 8c2 0 3.5-1 5.5-4Zm0 0c2 3 3.5 4 5.5 4a4 4 0 0 0 0-8c-2 0-3.5 1-5.5 4Z\"\/><\/svg><\/span><dl><dt>Strength<\/dt><dd>500 mg \/ 5 mL<\/dd><\/dl><\/li>\n      <li><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><path d=\"M21 8 12 3 3 8v8l9 5 9-5V8Z\"\/><path d=\"m3 8 9 5 9-5M12 13v8\"\/><\/svg><\/span><dl><dt>Presentations<\/dt><dd>Boxes of 5 or 50 ampoules<\/dd><\/dl><\/li>\n      <li><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><rect x=\"5\" y=\"3\" width=\"14\" height=\"18\" rx=\"3\"\/><path d=\"M9 8h6M9 12h6M9 16h3\"\/><\/svg><\/span><dl><dt>Standard<\/dt><dd>British Pharmacopoeia<\/dd><\/dl><\/li>\n    <\/ul>\n  <\/div>\n<\/div>\n\n<section class=\"about\" aria-labelledby=\"what\">\n  <div class=\"cx-wrap split\">\n    <div class=\"prose rv\">\n    <h2 class=\"h2\" id=\"what\">What is Plaxam?<\/h2>\n    <p><strong>PLAXAM<\/strong> is a tranexamic acid injection that helps prevent and treat haemorrhage associated with general or local fibrinolysis, according to the approved product information.<\/p>\n    <\/div>\n    <div class=\"media-wrap rv\" style=\"--d:1\"><div class=\"media\"><img loading=\"lazy\" src=\"https:\/\/crassulapharma.com\/wp-content\/uploads\/2026\/10\/info-plaxam.jpg\" alt=\"\" width=\"1600\" height=\"1200\" loading=\"lazy\" decoding=\"async\" title=\"\"><\/div><\/div>\n  <\/div>\n<\/section>\n\n<section class=\"indications\" id=\"indications\" aria-labelledby=\"ind\">\n  <div class=\"cx-wrap\">\n    <h2 class=\"h2 rv\" id=\"ind\">Indications<\/h2>\n    <p class=\"lead rv\">For prevention and treatment of haemorrhages due to general or local fibrinolysis in adults and children from one year of age.<\/p>\n    <div class=\"cards c2\">\n      <article class=\"card rv\" style=\"--d:0\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><circle cx=\"12\" cy=\"12\" r=\"9\"\/><path d=\"M12 7v5l3 2\"\/><\/svg><\/span><h3>Menorrhagia and Metrorrhagia<\/h3><\/div>\n        <p>Management of bleeding associated with general or local fibrinolysis.<\/p>\n      <\/article>\n      <article class=\"card rv\" style=\"--d:1\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><path d=\"M7 17 17 7M9 7h8v8\"\/><\/svg><\/span><h3>Surgical Procedures<\/h3><\/div>\n        <p>Including ENT, gynaecological, thoracic, abdominal and cardiovascular surgery.<\/p>\n      <\/article>\n      <article class=\"card rv\" style=\"--d:2\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><path d=\"M12 3s6 6.500 6 11a6 6 0 0 1-12 0c0-4.500 6-11 6-11Z\"\/><\/svg><\/span><h3>Gastrointestinal and Urinary Bleeding<\/h3><\/div>\n        <p>For haemorrhage in gastrointestinal or haemorrhagic urinary disorders when clinically indicated.<\/p>\n      <\/article>\n      <article class=\"card rv\" style=\"--d:3\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><path d=\"M12 3 4 6v6c0 4.500 3.400 7.800 8 9 4.600-1.200 8-4.500 8-9V6l-8-3Z\"\/><path d=\"m9 12 2 2 4-4\"\/><\/svg><\/span><h3>Fibrinolytic Agent-Related Haemorrhage<\/h3><\/div>\n        <p>Management of haemorrhage due to the administration of a fibrinolytic agent.<\/p>\n      <\/article>\n    <\/div>\n  <\/div>\n<\/section>\n\n<section class=\"presentations\" id=\"presentations\" aria-labelledby=\"pres\">\n  <div class=\"cx-wrap\">\n    <h2 class=\"h2 rv\" id=\"pres\">Presentations<\/h2>\n    <div class=\"cards pres4\">\n      <article class=\"pcard rv\" style=\"--c:#2c1b43;--d:0\"><div class=\"dose\">x5<\/div><dl class=\"pgrid\"><div><dd>5 ampoules of 5 mL<\/dd><\/div><\/dl><\/article>\n      <article class=\"pcard rv\" style=\"--c:#2c1b43;--d:1\"><div class=\"dose\">x50<\/div><dl class=\"pgrid\"><div><dd>50 ampoules of 5 mL<\/dd><\/div><\/dl><\/article>\n      <article class=\"pcard rv\" style=\"--c:#2c1b43;--d:2\"><dl class=\"pgrid\"><div><dt>Route<\/dt><dd>Slow intravenous injection<\/dd><\/div><\/dl><\/article>\n      <article class=\"pcard rv\" style=\"--c:#2c1b43;--d:3\"><dl class=\"pgrid\"><div><dt>Shelf life<\/dt><dd>36 months<\/dd><\/div><\/dl><\/article>\n    <\/div>\n  <\/div>\n<\/section>\n\n<section id=\"mechanism\" aria-labelledby=\"moa\">\n  <div class=\"cx-wrap\">\n    <h2 class=\"h2 rv\" id=\"moa\">Pharmacological Properties<\/h2>\n    <div class=\"mech-grid one\">\n      <p class=\"mech-text rv\">Tranexamic acid exerts anti-haemorrhagic activity by inhibiting the fibrinolytic properties of plasmin.<\/p>\n      <ol class=\"steps\" id=\"steps\" hidden><\/ol>\n\n      <div class=\"flow\" id=\"flow\" role=\"group\" aria-label=\"How Plaxam works\">\n        <p class=\"flow-title\">How Plaxam works<\/p>\n        <span class=\"node primary\" style=\"--i:0\">Plaxam\u00ae<small>Tranexamic Acid<\/small><\/span>\n        <div class=\"link-v\" style=\"--i:1\"><\/div>\n        <span class=\"node\" style=\"--i:2\">Binds to Plasminogen<\/span>\n        <div class=\"link-v\" style=\"--i:3\"><\/div>\n        <span class=\"node\" style=\"--i:4\">Inhibits Plasmin Fibrinolytic Activity<\/span>\n        <div class=\"link-v\" style=\"--i:5\"><\/div>\n        <span class=\"node end g\" style=\"--i:6\">Helps Stabilise Fibrin Clot<\/span>\n      <\/div>\n    <\/div>\n\n    <div class=\"cards c2\" style=\"margin-top:56px\">\n      <article class=\"card rv\" style=\"--d:0\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><circle cx=\"12\" cy=\"12\" r=\"9\"\/><path d=\"M12 7v5l3 2\"\/><\/svg><\/span><h3>Dosage and Administration<\/h3><\/div>\n        <ul><li>For local fibrinolysis: 0.5 g (one 5 mL ampoule) by slow intravenous injection, two to three times daily, unless otherwise prescribed.<\/li><li>For general fibrinolysis: 1 g (two 5 mL ampoules) by slow intravenous injection every 6 to 8 hours, equivalent to 15 mg\/kg body weight.<\/li><li>Administration is strictly limited to slow intravenous injection. Do not administer by the intramuscular route.<\/li><\/ul>\n      <\/article>\n      <article class=\"card rv\" style=\"--d:1\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><rect x=\"2.5\" y=\"8\" width=\"19\" height=\"8\" rx=\"4\"\/><path d=\"M12 8v8\"\/><\/svg><\/span><h3>Benefits and Clinical Considerations<\/h3><\/div>\n        <div class=\"sub\"><h4>Targeted Antifibrinolytic Action<\/h4><p>By inhibiting plasmin fibrinolytic activity, tranexamic acid helps preserve fibrin clot stability.<\/p>\n        <h4>Renal Elimination<\/h4><p>Tranexamic acid is excreted mainly unchanged in urine; reduce dosage in mild to moderate renal impairment and do not use in severe renal impairment.<\/p><\/div>\n      <\/article>\n    <\/div>\n  <\/div>\n<\/section>\n\n<section class=\"note\" aria-labelledby=\"imp\">\n  <div class=\"cx-wrap\">\n    <div class=\"note-box has-bg rv\" style=\"--ov:62,11,46\">\n      <div class=\"bg\" aria-hidden=\"true\"><img loading=\"lazy\" src=\"https:\/\/crassulapharma.com\/wp-content\/uploads\/2026\/10\/info-plaxam.jpg\" alt=\"\" width=\"1600\" height=\"1200\" loading=\"lazy\" decoding=\"async\" title=\"\"><\/div>\n      <h3 id=\"imp\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><path d=\"M12 3 2.500 20h19L12 3Z\"\/><path d=\"M12 10v4.500M12 17.200v.1\"\/><\/svg><\/span>Safety and Precautionary Measures<\/h3>\n      <div class=\"two\">\n        <div class=\"sub\"><h4>Thrombotic Risk<\/h4><p>Contraindicated in acute venous or arterial thrombosis. Assess thromboembolic risk factors before use.<\/p><\/div>\n        <div class=\"sub\"><h4>Important Warnings<\/h4><p>Use slow intravenous injection only. Contraindicated in severe renal impairment and history of convulsions. Monitor possible visual disturbances.<\/p><\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/section>\n\n<section class=\"faq\" id=\"faq\" aria-labelledby=\"faq-h\">\n  <div class=\"cx-wrap\">\n    <h2 class=\"h2 rv\" id=\"faq-h\">Frequently Asked Questions<\/h2>\n    <div class=\"faq-list\">\n      <div class=\"faq-item rv\" style=\"--d:0\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q1\" aria-expanded=\"false\" aria-controls=\"faq-a1\"><span>What is Plaxam?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a1\" role=\"region\" aria-labelledby=\"faq-q1\"><div><p><strong>PLAXAM<\/strong> is a tranexamic acid injection that helps prevent and treat haemorrhage associated with general or local fibrinolysis, according to the approved product information.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:1\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q2\" aria-expanded=\"false\" aria-controls=\"faq-a2\"><span>What is Plaxam indicated for?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a2\" role=\"region\" aria-labelledby=\"faq-q2\"><div><p>For prevention and treatment of haemorrhages due to general or local fibrinolysis in adults and children from one year of age. This includes menorrhagia and metrorrhagia (management of bleeding associated with general or local fibrinolysis), surgical procedures (including ENT, gynaecological, thoracic, abdominal and cardiovascular surgery), gastrointestinal and urinary bleeding (for haemorrhage in gastrointestinal or haemorrhagic urinary disorders when clinically indicated) and fibrinolytic agent-related haemorrhage (management of haemorrhage due to the administration of a fibrinolytic agent).<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:2\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q3\" aria-expanded=\"false\" aria-controls=\"faq-a3\"><span>How does Plaxam work?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a3\" role=\"region\" aria-labelledby=\"faq-q3\"><div><p>Tranexamic acid exerts anti-haemorrhagic activity by inhibiting the fibrinolytic properties of plasmin. By inhibiting plasmin fibrinolytic activity, tranexamic acid helps preserve fibrin clot stability.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:3\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q4\" aria-expanded=\"false\" aria-controls=\"faq-a4\"><span>How is Plaxam dosed and administered?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a4\" role=\"region\" aria-labelledby=\"faq-q4\"><div><p>For local fibrinolysis: 0.5 g (one 5 mL ampoule) by slow intravenous injection, two to three times daily, unless otherwise prescribed. For general fibrinolysis: 1 g (two 5 mL ampoules) by slow intravenous injection every 6 to 8 hours, equivalent to 15 mg\/kg body weight. Administration is strictly limited to slow intravenous injection. Do not administer by the intramuscular route.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:4\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q5\" aria-expanded=\"false\" aria-controls=\"faq-a5\"><span>How is Plaxam eliminated?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a5\" role=\"region\" aria-labelledby=\"faq-q5\"><div><p>Tranexamic acid is excreted mainly unchanged in urine; reduce dosage in mild to moderate renal impairment and do not use in severe renal impairment.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:4\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q6\" aria-expanded=\"false\" aria-controls=\"faq-a6\"><span>What are the safety and precautionary measures for Plaxam?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a6\" role=\"region\" aria-labelledby=\"faq-q6\"><div><p>Contraindicated in acute venous or arterial thrombosis. Assess thromboembolic risk factors before use. Use slow intravenous injection only. Contraindicated in severe renal impairment and history of convulsions. Monitor possible visual disturbances.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:4\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q7\" aria-expanded=\"false\" aria-controls=\"faq-a7\"><span>Which strength and presentations are available?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a7\" role=\"region\" aria-labelledby=\"faq-q7\"><div><p>Plaxam contains tranexamic acid 500 mg \/ 5 mL and is presented in boxes of 5 or 50 ampoules (5 ampoules of 5 mL or 50 ampoules of 5 mL) for slow intravenous injection. The shelf life is 36 months.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:4\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q8\" aria-expanded=\"false\" aria-controls=\"faq-a8\"><span>How is Plaxam manufactured?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a8\" role=\"region\" aria-labelledby=\"faq-q8\"><div><p>Each 5 mL amber glass ampoule contains tranexamic acid BP 500 mg as a clear, colourless injection. The finished-product specification includes BP identity, assay, pH, related substances and bacterial endotoxins testing. Crassula Pharma certifies that all our products are manufactured in accordance with GMP parameters.<\/p><\/div><\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/section>\n\n<section class=\"quality\" id=\"quality\" aria-labelledby=\"qs\">\n  <div class=\"cx-wrap\">\n    <div class=\"qbox rv\">\n      <h2 id=\"qs\">Quality and Standards<\/h2>\n      <div class=\"qgrid one\">\n        <img decoding=\"async\" class=\"gmp\" src=\"https:\/\/crassulapharma.com\/wp-content\/uploads\/2026\/10\/logo-gmp.png\" alt=\"GMP Certified Quality\" width=\"112\" height=\"112\" title=\"\">\n        <div class=\"check\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><circle cx=\"12\" cy=\"12\" r=\"9.5\"\/><path d=\"m8 12.5 2.7 2.7L16 9.5\"\/><\/svg><p>Each 5 mL amber glass ampoule contains tranexamic acid BP 500 mg as a clear, colourless injection. The finished-product specification includes BP identity, assay, pH, related substances and bacterial endotoxins testing.<\/p><\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/section>\n<\/main>\n\n\n<script>\n(function(){\n  var d=document.documentElement,b=document.body;\n  b.classList.remove('no-js');\n  requestAnimationFrame(function(){requestAnimationFrame(function(){b.classList.add('loaded')})});\n\n  var io=new IntersectionObserver(function(es){es.forEach(function(e){\n    if(e.isIntersecting){e.target.classList.add('in');io.unobserve(e.target)}})},{threshold:.15,rootMargin:'0px 0px -6% 0px'});\n  document.querySelectorAll('.rv').forEach(function(el){io.observe(el)});\n\n\n  (function(){\n    var c=document.getElementById('fx');if(!c||!c.getContext)return;\n    var ctx=c.getContext('2d'),hero=c.parentElement,W=0,H=0,dpr=1,P=[],run=false,raf=0,mx=-999,my=-999;\n    var reduce=matchMedia('(prefers-reduced-motion: reduce)').matches;\n    function size(){var r=hero.getBoundingClientRect();dpr=Math.min(devicePixelRatio||1,2);W=r.width;H=r.height;c.width=W*dpr;c.height=H*dpr;ctx.setTransform(dpr,0,0,dpr,0,0);\n      var n=Math.round(Math.min(90,Math.max(28,W*H\/16000)));P=[];\n      for(var i=0;i<n;i++)P.push({x:Math.random()*W,y:Math.random()*H,vx:(Math.random()-.5)*.28,vy:(Math.random()-.5)*.28,r:Math.random()*1.4+.8});}\n    function draw(){\n      ctx.clearRect(0,0,W,H);var L=Math.min(150,W\/7);\n      for(var i=0;i<P.length;i++){var a=P[i];\n        if(!reduce){a.x+=a.vx;a.y+=a.vy;if(a.x<0||a.x>W)a.vx*=-1;if(a.y<0||a.y>H)a.vy*=-1;\n          var dx=a.x-mx,dy=a.y-my,d=dx*dx+dy*dy;if(d<14400){var f=(1-Math.sqrt(d)\/120)*.6;a.x+=dx*f*.02;a.y+=dy*f*.02}}\n        for(var j=i+1;j<P.length;j++){var b=P[j],ex=a.x-b.x,ey=a.y-b.y,e=ex*ex+ey*ey;\n          if(e<L*L){ctx.strokeStyle='rgba(224,196,236,'+(.22*(1-Math.sqrt(e)\/L))+')';ctx.lineWidth=1;ctx.beginPath();ctx.moveTo(a.x,a.y);ctx.lineTo(b.x,b.y);ctx.stroke()}}\n        ctx.fillStyle='rgba(240,222,247,.75)';ctx.beginPath();ctx.arc(a.x,a.y,a.r,0,6.2832);ctx.fill();}\n      if(run&&!reduce)raf=requestAnimationFrame(draw);}\n    function start(){if(!run){run=true;raf=requestAnimationFrame(draw)}}\n    function stop(){run=false;cancelAnimationFrame(raf)}\n    size();draw();\n    var rt;addEventListener('resize',function(){clearTimeout(rt);rt=setTimeout(function(){size();draw()},150)});\n    hero.addEventListener('pointermove',function(e){var r=hero.getBoundingClientRect();mx=e.clientX-r.left;my=e.clientY-r.top},{passive:true});\n    hero.addEventListener('pointerleave',function(){mx=my=-999});\n    new IntersectionObserver(function(es){es[0].isIntersecting?start():stop()}).observe(hero);\n  })();\n\n  document.querySelectorAll('.faq-q').forEach(function(b){\n    b.addEventListener('click',function(){\n      var it=b.closest('.faq-item'),open=it.classList.toggle('open');\n      b.setAttribute('aria-expanded',open?'true':'false');\n    });\n  });\n  var flow=document.getElementById('flow');\n  var fio=new IntersectionObserver(function(es){es.forEach(function(e){if(e.isIntersecting){flow.classList.add('in');fio.disconnect()}})},{threshold:.25});\n  fio.observe(flow);\n\n  var steps=document.getElementById('steps');\n  function line(){var r=steps.getBoundingClientRect(),h=innerHeight;\n    var p=Math.min(1,Math.max(0,(h*.75-r.top)\/r.height));steps.style.setProperty('--line',p)}\n  addEventListener('scroll',line,{passive:true});line();\n\n})();\n<\/script>\n<\/body>\n<\/html>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Plaxam\u00ae (Tranexamic Acid) \u2013 Crassula Skip to content Antifibrinolytic \u00b7 Haemorrhage Management Plaxam\u00ae Tranexamic Acid 500 mg \/ 5 mL Pharmacological Properties Active ingredient Tranexamic Acid Strength 500 mg \/ 5 mL Presentations Boxes of 5 or 50 ampoules Standard British Pharmacopoeia What is Plaxam? PLAXAM is a tranexamic acid injection that helps prevent and [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"class_list":["post-11991","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/pages\/11991","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/comments?post=11991"}],"version-history":[{"count":7,"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/pages\/11991\/revisions"}],"predecessor-version":[{"id":12001,"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/pages\/11991\/revisions\/12001"}],"wp:attachment":[{"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/media?parent=11991"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}