{"id":11880,"date":"2026-10-20T18:18:09","date_gmt":"2026-10-20T22:18:09","guid":{"rendered":"https:\/\/crassulapharma.com\/?page_id=11880"},"modified":"2026-10-22T13:36:42","modified_gmt":"2026-10-22T17:36:42","slug":"estarol-duo","status":"publish","type":"page","link":"https:\/\/crassulapharma.com\/es\/estarol-duo\/","title":{"rendered":"Estarol Duo"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"11880\" class=\"elementor elementor-11880\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3476d1b e-con-full e-flex e-con e-parent\" data-id=\"3476d1b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ef89a49 elementor-widget elementor-widget-html\" data-id=\"ef89a49\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<!doctype html>\n<html lang=\"en\">\n<head>\n<meta charset=\"utf-8\">\n<meta name=\"viewport\" content=\"width=device-width, initial-scale=1\">\n<title>Estarol Duo\u00ae (Atorvastatin \/ Ezetimibe) \u2013 Crassula<\/title>\n<meta name=\"description\" content=\"Estarol Duo is a combination of Atorvastatin and Ezetimibe, presented in oral-release tablets for the effective management of cholesterol. Each tablet combines these two molecules to improve lipid profile control in patients with hypercholesterolemia.\">\n<link rel=\"preload\" href=\"fonts\/poppins-latin-600-normal.woff2\" as=\"font\" type=\"font\/woff2\" crossorigin>\n<link rel=\"preload\" href=\"fonts\/ibm-plex-sans-latin-400-normal.woff2\" as=\"font\" type=\"font\/woff2\" crossorigin>\n<style>\n@font-face{font-family:\"Poppins\";font-weight:500;font-style:normal;font-display:swap;src:url(fonts\/poppins-latin-500-normal.woff2) format(\"woff2\")}\n@font-face{font-family:\"Poppins\";font-weight:600;font-style:normal;font-display:swap;src:url(fonts\/poppins-latin-600-normal.woff2) format(\"woff2\")}\n@font-face{font-family:\"IBM Plex Sans\";font-weight:400;font-style:normal;font-display:swap;src:url(fonts\/ibm-plex-sans-latin-400-normal.woff2) format(\"woff2\")}\n@font-face{font-family:\"IBM Plex Sans\";font-weight:500;font-style:normal;font-display:swap;src:url(fonts\/ibm-plex-sans-latin-500-normal.woff2) 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li:first-child{flex:1.6}\n[type=\"button\"]:hover{background-color:transparent;color:var(--teal-head)}\n[type=\"button\"]:focus{background-color:transparent;color:var(--teal-head)}\n<\/style>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"What is Estarol Duo?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Estarol Duo is a combination of Atorvastatin and Ezetimibe, presented in oral-release tablets for the effective management of cholesterol. Each tablet combines these two molecules to improve lipid profile control in patients with hypercholesterolemia.\"}}, {\"@type\": \"Question\", \"name\": \"What is Estarol Duo indicated for?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Estarol Duo is indicated for the treatment of high cholesterol in adults and to reduce the risk of cardiovascular events in patients who have not responded adequately to diets or other treatments. It is suitable for primary hypercholesterolemia, mixed hyperlipidemia, prevention of cardiovascular disease, post-cardiovascular event therapy and, according to medical evaluation, familial hypercholesterolemia.\"}}, {\"@type\": \"Question\", \"name\": \"How does Estarol Duo work?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Atorvastatin is a competitive inhibitor of HMG-CoA reductase, the key enzyme in cholesterol biosynthesis. Ezetimibe inhibits the intestinal absorption of cholesterol, complementing the action of atorvastatin. The combined action provides a significant reduction in LDL and total cholesterol levels.\"}}, {\"@type\": \"Question\", \"name\": \"How is Estarol Duo dosed and administered?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"The dose should be adjusted according to cholesterol levels and the patient\u2019s response. Typical starting dose: one tablet daily, preferably at night, to take advantage of the body\u2019s natural cholesterol synthesis cycle. Can be taken with or without food.\"}}, {\"@type\": \"Question\", \"name\": \"What are the benefits of the Atorvastatin and Ezetimibe combination?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"The combination in a single tablet facilitates treatment adherence, simplifying the patient\u2019s medication regimen. Improves the lipid profile more effectively than the use of each component separately.\"}}, {\"@type\": \"Question\", \"name\": \"What are the clinical considerations for Estarol Duo?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Use only when the benefits outweigh the risks. Verify that the patient has tried to modify their diet and lifestyle before prescribing. Initiate and adjust treatment under medical supervision, considering the patient\u2019s response and tolerance.\"}}, {\"@type\": \"Question\", \"name\": \"What are the safety and precautionary measures for Estarol Duo?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Monitor blood lipid levels and adjust the dose as necessary. Use with caution in patients with a history of liver disease. Contraindicated in patients with active liver disease or unexplained persistent elevation of serum transaminases.\"}}, {\"@type\": \"Question\", \"name\": \"Which strengths and presentation are available?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Estarol Duo is available as Atorvastatin 10 mg \/ Ezetimibe 10 mg and Atorvastatin 20 mg \/ Ezetimibe 10 mg, in a box of 30 or 100 tablets, following the United States Pharmacopeia standard.\"}}, {\"@type\": \"Question\", \"name\": \"How is Estarol Duo manufactured?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Estarol Duo is manufactured according to the strict specifications of the United States Pharmacopeia to ensure consistency and superior quality. Crassula Pharma certifies that all its products are manufactured in accordance with GMP parameters.\"}}]}<\/script>\n<\/head>\n<body class=\"no-js\">\n<a class=\"skip\" href=\"#main\">Skip to content<\/a>\n<span id=\"top\"><\/span>\n\n\n<main id=\"main\">\n<section class=\"hero\" aria-labelledby=\"h1\" style=\"padding:0\">\n  <canvas id=\"fx\" aria-hidden=\"true\"><\/canvas>\n  <div class=\"cx-wrap\">\n    <div class=\"hero-copy\">\n      <span class=\"tag\">Combination Therapy \u00b7 Hypercholesterolemia<\/span>\n      <h1 id=\"h1\">Estarol Duo<sup>\u00ae<\/sup><\/h1>\n      <p class=\"generic\">Atorvastatin \/ Ezetimibe<\/p>\n      <div class=\"strengths\" role=\"list\">\n        <span class=\"chip t\" role=\"listitem\">10 mg \/ 10 mg<\/span>\n        <span class=\"chip g\" role=\"listitem\">20 mg \/ 10 mg<\/span>\n      <\/div>\n      <div class=\"cta-row\">\n        <a class=\"btn btn-primary\" href=\"#mechanism\">Pharmacological Properties<\/a>\n      <\/div>\n    <\/div>\n    <div class=\"hero-art\">\n      <img fetchpriority=\"high\" decoding=\"async\" class=\"a\" src=\"https:\/\/crassulapharma.com\/wp-content\/uploads\/2026\/10\/box-estarol-duo-20.png\" alt=\"Estarol Duo atorvastatin \/ ezetimibe 20 mg \/ 10 mg box\" width=\"675\" height=\"407\" title=\"\">\n      <img decoding=\"async\" class=\"b\" src=\"https:\/\/crassulapharma.com\/wp-content\/uploads\/2026\/10\/box-estarol-duo-10.png\" alt=\"Estarol Duo atorvastatin \/ ezetimibe 10 mg \/ 10 mg box\" width=\"766\" height=\"482\" title=\"\">\n    <\/div>\n  <\/div>\n<\/section>\n\n<div class=\"specs\">\n  <div class=\"cx-wrap\">\n    <ul>\n      <li><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><rect x=\"2.5\" y=\"8\" width=\"19\" height=\"8\" rx=\"4\"\/><path d=\"M12 8v8\"\/><\/svg><\/span><dl><dt>Active ingredients<\/dt><dd>Atorvastatin + Ezetimibe<\/dd><\/dl><\/li>\n      <li><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><path d=\"M12 12c-2-3-3.5-4-5.5-4a4 4 0 0 0 0 8c2 0 3.5-1 5.5-4Zm0 0c2 3 3.5 4 5.5 4a4 4 0 0 0 0-8c-2 0-3.5 1-5.5 4Z\"\/><\/svg><\/span><dl><dt>Strengths<\/dt><dd>10\/10 mg \u00b7 20\/10 mg<\/dd><\/dl><\/li>\n      <li><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><path d=\"M21 8 12 3 3 8v8l9 5 9-5V8Z\"\/><path d=\"m3 8 9 5 9-5M12 13v8\"\/><\/svg><\/span><dl><dt>Presentation<\/dt><dd>Box of 30 or 100 tablets<\/dd><\/dl><\/li>\n      <li><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><rect x=\"5\" y=\"3\" width=\"14\" height=\"18\" rx=\"3\"\/><path d=\"M9 8h6M9 12h6M9 16h3\"\/><\/svg><\/span><dl><dt>Standard<\/dt><dd>USP<\/dd><\/dl><\/li>\n    <\/ul>\n  <\/div>\n<\/div>\n\n<section class=\"about\" aria-labelledby=\"what\">\n  <div class=\"cx-wrap split\">\n    <div class=\"prose rv\">\n    <h2 class=\"h2\" id=\"what\">What is Estarol Duo?<\/h2>\n    <p><strong>Estarol Duo<\/strong> is a combination of Atorvastatin and Ezetimibe, presented in oral-release tablets for the effective management of cholesterol. Each tablet combines these two molecules to improve lipid profile control in patients with hypercholesterolemia.<\/p>\n    <\/div>\n    <div class=\"media-wrap rv\" style=\"--d:1\"><div class=\"media\"><img loading=\"lazy\" src=\"https:\/\/crassulapharma.com\/wp-content\/uploads\/2026\/10\/info-estarol-duo.jpg\" alt=\"\" width=\"1600\" height=\"1200\" loading=\"lazy\" decoding=\"async\" title=\"\"><\/div><\/div>\n  <\/div>\n<\/section>\n\n<section class=\"indications\" id=\"indications\" aria-labelledby=\"ind\">\n  <div class=\"cx-wrap\">\n    <h2 class=\"h2 rv\" id=\"ind\">Indications<\/h2>\n    <p class=\"lead rv\">Estarol Duo is indicated for the treatment of high cholesterol in adults and to reduce the risk of cardiovascular events in patients who have not responded adequately to diets or other treatments. It is suitable for treatment in the following conditions:<\/p>\n    <div class=\"cards c3\" style=\"margin-bottom:20px\">\n      <article class=\"card rv\" style=\"--d:0\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><path d=\"M3 17l5-6 4 4 8-9\"\/><path d=\"M15 6h5v5\"\/><\/svg><\/span><h3>Primary Hypercholesterolemia<\/h3><\/div>\n        <p>To reduce elevated LDL and total cholesterol levels.<\/p>\n      <\/article>\n      <article class=\"card rv\" style=\"--d:1\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><circle cx=\"8\" cy=\"8\" r=\"4\"\/><circle cx=\"16\" cy=\"16\" r=\"4\"\/><path d=\"m11 11 2 2\"\/><\/svg><\/span><h3>Mixed Hyperlipidemia<\/h3><\/div>\n        <p>Treatment of patients with multiple types of dyslipidemia.<\/p>\n      <\/article>\n      <article class=\"card rv\" style=\"--d:2\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><path d=\"M12 20s-7-4.5-7-10a4 4 0 0 1 7-2.5A4 4 0 0 1 19 10c0 5.500-7 10-7 10Z\"\/><\/svg><\/span><h3>Prevention of Cardiovascular Disease<\/h3><\/div>\n        <p>Reduces the risk of cardiovascular events in patients with coronary heart disease and a history of acute coronary syndrome.<\/p>\n      <\/article>\n    <\/div>\n    <div class=\"cards c2\" style=\"margin-bottom:0\">\n      <article class=\"card rv\" style=\"--d:0\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><path d=\"M12 3 4 6v6c0 4.500 3.500 7.500 8 9 4.500-1.500 8-4.500 8-9V6l-8-3Z\"\/><path d=\"m8.500 12 2.500 2.500L15.500 10\"\/><\/svg><\/span><h3>Post-Cardiovascular Event<\/h3><\/div>\n        <p>As part of lipid-lowering therapy in patients with established coronary heart disease.<\/p>\n      <\/article>\n      <article class=\"card rv\" style=\"--d:1\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><circle cx=\"12\" cy=\"12\" r=\"9\"\/><path d=\"M12 8v5M12 16v.1\"\/><\/svg><\/span><h3>Other Related Conditions<\/h3><\/div>\n        <p>According to medical evaluation in cases of familial hypercholesterolemia.<\/p>\n      <\/article>\n    <\/div>\n  <\/div>\n<\/section>\n\n<section class=\"presentations\" id=\"presentations\" aria-labelledby=\"pres\">\n  <div class=\"cx-wrap\">\n    <h2 class=\"h2 rv\" id=\"pres\">Presentations<\/h2>\n    <div class=\"pres\">\n      <article class=\"pcard rv\" style=\"--c:#d22378;--d:0\">\n        <div class=\"dose\">10\/10<small>mg<\/small><\/div>\n        <div><h3>Atorvastatin 10 mg \/ Ezetimibe 10 mg<\/h3><p>Box of 30 or 100 tablets \u00b7 United States Pharmacopeia<\/p><\/div>\n      <\/article>\n      <article class=\"pcard a2 rv\" style=\"--d:1\">\n        <div class=\"dose\">20\/10<small>mg<\/small><\/div>\n        <div><h3>Atorvastatin 20 mg \/ Ezetimibe 10 mg<\/h3><p>Box of 30 or 100 tablets \u00b7 United States Pharmacopeia<\/p><\/div>\n      <\/article>\n    <\/div>\n  <\/div>\n<\/section>\n\n<section id=\"mechanism\" aria-labelledby=\"moa\">\n  <div class=\"cx-wrap\">\n    <h2 class=\"h2 rv\" id=\"moa\">Pharmacological Properties<\/h2>\n    <div class=\"mech-grid\">\n      <ol class=\"steps\" id=\"steps\">\n        <li class=\"rv\"><span class=\"num\">1<\/span><h3>Atorvastatin<\/h3><p>Atorvastatin is a competitive inhibitor of HMG-CoA reductase, the key enzyme in cholesterol biosynthesis.<\/p><\/li>\n        <li class=\"rv\"><span class=\"num\">2<\/span><h3>Ezetimibe<\/h3><p>Ezetimibe inhibits the intestinal absorption of cholesterol, complementing the action of atorvastatin.<\/p><\/li>\n        <li class=\"rv\"><span class=\"num\">3<\/span><h3>Combined Action<\/h3><p>The combined action provides a significant reduction in LDL and total cholesterol levels.<\/p><\/li>\n      <\/ol>\n\n      <div class=\"flow\" id=\"flow\" role=\"group\" aria-label=\"How Estarol Duo works\">\n        <p class=\"flow-title\">How Estarol Duo works<\/p>\n        <span class=\"node primary\" style=\"--i:0\">Estarol Duo\u00ae<\/span>\n        <div class=\"fork\" style=\"--i:1;max-width:360px\"><i><\/i><i><\/i><\/div>\n        <div class=\"cols\">\n          <div class=\"col\">\n            <span class=\"node blue\" style=\"--i:2\">Atorvastatin<\/span>\n            <div class=\"link-v stop\" style=\"--i:3;height:34px\"><span>inhibits<\/span><\/div>\n            <span class=\"node\" style=\"--i:4\">HMG-CoA reductase<small>cholesterol biosynthesis<\/small><\/span>\n            <div class=\"link-v\" style=\"--i:5\"><\/div>\n            <span class=\"node\" style=\"--i:6\"><span class=\"dn\">\u2193<\/span> Cholesterol synthesis<\/span>\n            <div class=\"link-v nohead\" style=\"--i:7\"><\/div>\n          <\/div>\n          <div class=\"col\">\n            <span class=\"node lime\" style=\"--i:2\">Ezetimibe<\/span>\n            <div class=\"link-v stop\" style=\"--i:3;height:34px\"><span>inhibits<\/span><\/div>\n            <span class=\"node\" style=\"--i:4\">Intestinal cholesterol absorption<\/span>\n            <div class=\"link-v\" style=\"--i:5\"><\/div>\n            <span class=\"node\" style=\"--i:6\"><span class=\"dn\">\u2193<\/span> Cholesterol absorption<\/span>\n            <div class=\"link-v nohead\" style=\"--i:7\"><\/div>\n          <\/div>\n        <\/div>\n        <div class=\"join\" style=\"--i:8\"><\/div>\n        <div style=\"height:14px\"><\/div>\n        <span class=\"node end\" style=\"--i:9\"><span class=\"dn\">\u2193<\/span> LDL &amp; total cholesterol<\/span>\n      <\/div>\n    <\/div>\n\n    <div class=\"cards c2\" style=\"margin-top:56px\">\n      <article class=\"card rv\" style=\"--d:0\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><circle cx=\"12\" cy=\"12\" r=\"9\"\/><path d=\"M12 7v5l3 2\"\/><\/svg><\/span><h3>Dosage and Administration<\/h3><\/div>\n        <ul><li>The dose should be adjusted according to cholesterol levels and the patient\u2019s response.<\/li><li>Typical starting dose: one tablet daily, preferably at night, to take advantage of the body\u2019s natural cholesterol synthesis cycle.<\/li><li>Can be taken with or without food.<\/li><\/ul>\n      <\/article>\n      <article class=\"card rv\" style=\"--d:1\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><rect x=\"2.5\" y=\"8\" width=\"19\" height=\"8\" rx=\"4\"\/><path d=\"M12 8v8\"\/><\/svg><\/span><h3>Benefits of the Atorvastatin and Ezetimibe Combination<\/h3><\/div>\n        <ul><li>The combination in a single tablet facilitates treatment adherence, simplifying the patient\u2019s medication regimen.<\/li><li>Improves the lipid profile more effectively than the use of each component separately.<\/li><\/ul>\n      <\/article>\n      <article class=\"card wide rv\" style=\"--d:2\">\n        <div class=\"card-h\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><path d=\"M9 3h6M10 3v6l-5 9a2 2 0 0 0 1.800 3h10.400a2 2 0 0 0 1.800-3l-5-9V3\"\/><path d=\"M7.500 15h9\"\/><\/svg><\/span><h3>Clinical Considerations<\/h3><\/div>\n        <ul><li>Use only when the benefits outweigh the risks.<\/li><li>Verify that the patient has tried to modify their diet and lifestyle before prescribing.<\/li><li>Initiate and adjust treatment under medical supervision, considering the patient\u2019s response and tolerance.<\/li><\/ul>\n      <\/article>\n    <\/div>\n  <\/div>\n<\/section>\n\n<section class=\"note\" aria-labelledby=\"imp\">\n  <div class=\"cx-wrap\">\n    <div class=\"note-box has-bg rv\" style=\"--ov:12,36,59\">\n      <div class=\"bg\" aria-hidden=\"true\"><img loading=\"lazy\" src=\"https:\/\/crassulapharma.com\/wp-content\/uploads\/2026\/10\/info-estarol-duo.jpg\" alt=\"\" width=\"1600\" height=\"1200\" loading=\"lazy\" decoding=\"async\" title=\"\"><\/div>\n      <h3 id=\"imp\"><span class=\"ico\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><path d=\"M12 3 2.500 20h19L12 3Z\"\/><path d=\"M12 10v4.500M12 17.200v.1\"\/><\/svg><\/span>Safety and Precautionary Measures<\/h3>\n      <ul>\n        <li>Monitor blood lipid levels and adjust the dose as necessary.<\/li>\n        <li>Use with caution in patients with a history of liver disease.<\/li>\n        <li>Contraindicated in patients with active liver disease or unexplained persistent elevation of serum transaminases.<\/li>\n      <\/ul>\n    <\/div>\n  <\/div>\n<\/section>\n\n<section class=\"faq\" id=\"faq\" aria-labelledby=\"faq-h\">\n  <div class=\"cx-wrap\">\n    <h2 class=\"h2 rv\" id=\"faq-h\">Frequently Asked Questions<\/h2>\n    <div class=\"faq-list\">\n      <div class=\"faq-item rv\" style=\"--d:0\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q1\" aria-expanded=\"false\" aria-controls=\"faq-a1\"><span>What is Estarol Duo?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a1\" role=\"region\" aria-labelledby=\"faq-q1\"><div><p><strong>Estarol Duo<\/strong> is a combination of Atorvastatin and Ezetimibe, presented in oral-release tablets for the effective management of cholesterol. Each tablet combines these two molecules to improve lipid profile control in patients with hypercholesterolemia.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:1\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q2\" aria-expanded=\"false\" aria-controls=\"faq-a2\"><span>What is Estarol Duo indicated for?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a2\" role=\"region\" aria-labelledby=\"faq-q2\"><div><p>Estarol Duo is indicated for the treatment of high cholesterol in adults and to reduce the risk of cardiovascular events in patients who have not responded adequately to diets or other treatments. It is suitable for primary hypercholesterolemia, mixed hyperlipidemia, prevention of cardiovascular disease, post-cardiovascular event therapy and, according to medical evaluation, familial hypercholesterolemia.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:2\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q3\" aria-expanded=\"false\" aria-controls=\"faq-a3\"><span>How does Estarol Duo work?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a3\" role=\"region\" aria-labelledby=\"faq-q3\"><div><p>Atorvastatin is a competitive inhibitor of HMG-CoA reductase, the key enzyme in cholesterol biosynthesis. Ezetimibe inhibits the intestinal absorption of cholesterol, complementing the action of atorvastatin. The combined action provides a significant reduction in LDL and total cholesterol levels.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:3\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q4\" aria-expanded=\"false\" aria-controls=\"faq-a4\"><span>How is Estarol Duo dosed and administered?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a4\" role=\"region\" aria-labelledby=\"faq-q4\"><div><p>The dose should be adjusted according to cholesterol levels and the patient\u2019s response. Typical starting dose: one tablet daily, preferably at night, to take advantage of the body\u2019s natural cholesterol synthesis cycle. Can be taken with or without food.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:4\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q5\" aria-expanded=\"false\" aria-controls=\"faq-a5\"><span>What are the benefits of the Atorvastatin and Ezetimibe combination?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a5\" role=\"region\" aria-labelledby=\"faq-q5\"><div><p>The combination in a single tablet facilitates treatment adherence, simplifying the patient\u2019s medication regimen. Improves the lipid profile more effectively than the use of each component separately.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:4\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q6\" aria-expanded=\"false\" aria-controls=\"faq-a6\"><span>What are the clinical considerations for Estarol Duo?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a6\" role=\"region\" aria-labelledby=\"faq-q6\"><div><p>Use only when the benefits outweigh the risks. Verify that the patient has tried to modify their diet and lifestyle before prescribing. Initiate and adjust treatment under medical supervision, considering the patient\u2019s response and tolerance.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:4\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q7\" aria-expanded=\"false\" aria-controls=\"faq-a7\"><span>What are the safety and precautionary measures for Estarol Duo?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a7\" role=\"region\" aria-labelledby=\"faq-q7\"><div><p>Monitor blood lipid levels and adjust the dose as necessary. Use with caution in patients with a history of liver disease. Contraindicated in patients with active liver disease or unexplained persistent elevation of serum transaminases.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:4\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q8\" aria-expanded=\"false\" aria-controls=\"faq-a8\"><span>Which strengths and presentation are available?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a8\" role=\"region\" aria-labelledby=\"faq-q8\"><div><p>Estarol Duo is available as Atorvastatin 10 mg \/ Ezetimibe 10 mg and Atorvastatin 20 mg \/ Ezetimibe 10 mg, in a box of 30 or 100 tablets, following the United States Pharmacopeia standard.<\/p><\/div><\/div>\n      <\/div>\n      <div class=\"faq-item rv\" style=\"--d:4\">\n        <h3><button class=\"faq-q\" type=\"button\" id=\"faq-q9\" aria-expanded=\"false\" aria-controls=\"faq-a9\"><span>How is Estarol Duo manufactured?<\/span><span class=\"faq-ico\" aria-hidden=\"true\"><svg viewBox=\"0 0 16 16\"><path d=\"M8 2v12M2 8h12\"\/><\/svg><\/span><\/button><\/h3>\n        <div class=\"faq-a\" id=\"faq-a9\" role=\"region\" aria-labelledby=\"faq-q9\"><div><p>Estarol Duo is manufactured according to the strict specifications of the United States Pharmacopeia to ensure consistency and superior quality. Crassula Pharma certifies that all its products are manufactured in accordance with GMP parameters.<\/p><\/div><\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/section>\n\n<section class=\"quality\" id=\"quality\" aria-labelledby=\"qs\">\n  <div class=\"cx-wrap\">\n    <div class=\"qbox rv\">\n      <h2 id=\"qs\">Quality &amp; Standards<\/h2>\n      <div class=\"qgrid\">\n        <img decoding=\"async\" class=\"gmp\" src=\"https:\/\/crassulapharma.com\/wp-content\/uploads\/2026\/10\/logo-gmp.png\" alt=\"GMP Certified Quality\" width=\"112\" height=\"112\" title=\"\">\n        <div class=\"check\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><circle cx=\"12\" cy=\"12\" r=\"9.5\"\/><path d=\"m8 12.5 2.7 2.7L16 9.5\"\/><\/svg><p>Manufactured according to the strict specifications of the United States Pharmacopeia to ensure consistency and superior quality.<\/p><\/div>\n        <div class=\"check\"><svg viewBox=\"0 0 24 24\" aria-hidden=\"true\"><circle cx=\"12\" cy=\"12\" r=\"9.5\"\/><path d=\"m8 12.5 2.7 2.7L16 9.5\"\/><\/svg><p>Crassula Pharma certifies that all our products are manufactured in accordance with GMP parameters.<\/p><\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/section>\n<\/main>\n\n\n<script>\n(function(){\n  var d=document.documentElement,b=document.body;\n  b.classList.remove('no-js');\n  requestAnimationFrame(function(){requestAnimationFrame(function(){b.classList.add('loaded')})});\n\n  var io=new IntersectionObserver(function(es){es.forEach(function(e){\n    if(e.isIntersecting){e.target.classList.add('in');io.unobserve(e.target)}})},{threshold:.15,rootMargin:'0px 0px -6% 0px'});\n  document.querySelectorAll('.rv').forEach(function(el){io.observe(el)});\n\n\n  (function(){\n    var c=document.getElementById('fx');if(!c||!c.getContext)return;\n    var ctx=c.getContext('2d'),hero=c.parentElement,W=0,H=0,dpr=1,P=[],run=false,raf=0,mx=-999,my=-999;\n    var reduce=matchMedia('(prefers-reduced-motion: reduce)').matches;\n    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Standard USP What is Estarol Duo? [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"class_list":["post-11880","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/pages\/11880","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/comments?post=11880"}],"version-history":[{"count":10,"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/pages\/11880\/revisions"}],"predecessor-version":[{"id":12118,"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/pages\/11880\/revisions\/12118"}],"wp:attachment":[{"href":"https:\/\/crassulapharma.com\/es\/wp-json\/wp\/v2\/media?parent=11880"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}